Faculty
Professor
Ph.D. in Life Sciences, National Tsing Hua University
Jointly appointed with Department of Biological Science and Technology, NCTU, Taiwan
Biography
Experience
Expertise
Publications
1998 - 2000
Academia Sinica, Postdoctoral Fellow
1997 - 1998
The Johns Hopkins University, Pre-doctoral Fellow
1998 -
National Tsing Hua University, Taiwan R.O.C., Ph.D. of Life Sciences
1992 -
National Tsing Hua University, Taiwan R.O.C., B.S. Physics
2021/02 -
Professor, Department of Electrophysics, National Yang Ming Chiao Tung University
2017 - 2017
Vice President, The first cross-strait workshop on frontiers interdisciplinary of biomedicine
2014/08 - 2016/07
Associate Vice President for International Affairs, National Chiao Tung university
2014 - 2014
Guest Editor of Applied Surface Science (SCI)
2011 - 2011
Vice Chairman of User Executive Committee of National Synchrotron Radiation Research Center, Taiwan
2010 - 2010
Visiting Professor, Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Canada
2008/08 - 2009/07
Vice Chairman, Department of Biological Science and Technology, National Chiao Tung University
2005 - 2009
Associate Research Fellow, Institute of Physics, Academia Sinica
2005/08 - 2008/07
Associate Professor, Department of Biotechnology, National Chiao Tung university
2005 - 2007
Associate Research Fellow, National Nano Device laboratories, Research and Development Team
2004/08 - 2005/07
Associate Professor, Department of Physics, National Dong Hwa University
2000/08 - 2004/07
Assistant Professor, Department of Physics, National Dong Hwa University
1998 - 2000
Postdoctoral Fellow, Academia Sinica
1997 - 1998
Pre-doctoral Fellow, Johns Hopkins University. Sep 1997 to Aug 1998. Advisors: Professors P. C. Huang and Ru-Chih C. Huang

Single molecular studies by scanning probe microscope and bio-photonics, soft condense matter and biological physics; biomaterials synthesis and characterization for protein folding and mechanism study, bio-nanotechnology application and new functional bio-nano-material development, Raman and fluorescence spectra. Molecular simulation for revealing inter-molecules interactions.

Peer Reviewed Journal articles: *: Corresponding author.

  1. Huang W.-T., Chang M.-C., Chu C.-Y., Chang C.-C., Li M.-C.*, Liu D.-M.*, Self-assembled Amphiphilic Chitosan: A Time-dependent anostructural Evolution and Associated Drug Encapsulation/Elution Mechanism (2019) Carbohydrate Polymers 215, 246–252 (IF: 5.158; 5 Years IF: 5.326; Ranking 2/72, Chemistry, Applied)
  2. Chang P.-C., Chang C.-Y., Jian W.-B.*, Yuan C.-J., Chen Y.-C., Chang C.-C.* , The fabrication and application of Ni-DNA nanowire-based nanoelectronic devices (2019) Nano Research https://doi.org/10.1007/s12274-019-2363-2 (IF: 7.994; 5 Years IF: 8.045; Ranking 13/146, Physics, Applied)
  3. Chang C.-Y., Chen W., Su C.-H., Chang P.-C., Huang Y.-T., Hsu K-C., Yuan C.-J. (袁俊傑), Chang C.-C. (張家靖)*, Enhanced Bioconjugation on Sputtered Palladium Nano-thin-film Electrode (2019) Appl. Phys. Lett. 114, 093702 (IF: 3.495; 5 Years IF: 3.386; Ranking 29/146, Physics, Applied)
  4. Lin Y.-Y., Chien Y., Chuang J.-H., Chang C.-C., Yang Y.-P., Lai Y.-H., Lo W.-L., Chien K.-H., Huo T.-I., Wang C.-Y., Development of a graphene oxide-incorporated polydimethylsiloxane membrane with hexagonal micropillar (2018) Int. J. Mol. Sci. (SCI IF:3.687; 5 Years IF: 3.878; Ranking 52/171, Chemistry, Multidisciplinary; citation 2)
  5. Chu H.-L., Lai J.-J., Wu L.-Y., Chang S.-L., Liu C.-M., Jian W.-B.*, Chen Y.-C.*, Yuan C.-J., Wu T.-S., Soo Y.-L, Di Ventra M., Chang C.-C.* Exploration and Characterization of the Memcapacitor and Memristor Properties of Ni-DNA Nanowire Devices (2017) NPG Asia Materials 9, e430. (SCI IF:9.157; 5 Years IF: 10.089; Ranking 17/275, Materials Science, Multidisciplinary; citation 1)
  6. Pandian SRK, Yuan C.-J., Lin C.-C., Wang W.-H., and Chang C.-C. *, DNA-based nanowires and nanodevices (2017) Advances in Physics: X 2:1, 22-34 (SCI; Sister Journal of Advances in Physics, Physics, Condensed Matter, Citation 1)
  7. Yu-Ling Lin Y.-L., Tsai N.-M., Hsieh C.-H., Ho S.-Y., Chang J., Wu H.-Y., Hsu M.-H., Chang C.-C., Liao K.-W.*, Jackson T.L.B., Mold D. E., Huang R.C.C.*, In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway (2016) Proc. Natl. Acad. Sci. 2016, 113, E7798-E7807 (SCI IF: 9.504; 5 Years IF: 10.359; Ranking 5/64, Multidisciplinary Sciences, Citation 1)
  8. Peng CH, Chuang JH, Wang ML, Jhan YY, Chien KH, Chung YC, Hung KH, Chang CC, Lee CK, Tseng WL, Hwang DK, Hsu CH, Lin TC, Chiou SH, Chen SJ*, Laminin modification subretinal bio-scaffold remodels retinal pigment epithelium-driven microenvironment in vitro and in vivo. (2016) Oncotarget 7, 64631-64648 (SCI IF: 5.168; 5 Years IF: 5.312; Ranking 44/217, Oncology; Citation: 6)
  9. Tu, L.-C., Wu, M.-C.*, Chu, H.-L., Chiang, Y.-P., Kuo, C.-L., Li, H.-Y., Chang, C.-C.*, Surface electromyography analysis of blepharoptosis correction by transconjunctival incisions (2016) J. Electromyogr. Kines. 28, 23-30. (SCI IF: 1.568; 5 Years IF: 2.074; Ranking 38/65, Rehabilitation).
  10. Chuang, H., Huang, L.-C. S., Kapoor, M., Liao, Y.-J., Yang, C.-L., Chang, C.-C., Wu, C.-Y., Hwu, J-R.*, Huang, T.-J.* and Hsu, M,-H, * Design and synthesis of pyridine-pyrazole-sulfonate derivatives as potential anti-HBV agents (2016) MedChemComm 7, 832-836 (SCI IF: 2.342; 5 Years IF: 2.331; Ranking 35/59, Chemistry, Medicinal; Citation: 5)
  11. Zhang, J.F., Liang, Y.-C., Lin, X.D., Zhu, X.Y., Yan, L., Li, S.L., Yang, X., Zhu, G.Y., Rogach, A.L., Yu, P.K.N., Shi, P., Tu, L.-C., Chang, C.-C.*, Zhang, X.H.*, Chen, X.F., Zhang, W.J., and Lee, C.-S.* (2015) Self-Monitoring and Self-Delivery of Photosensitizer-Doped Nanoparticles for Highly Effective Combination Cancer Therapy in Vitro and in Vivo, ACS Nano, 9, 9741-9756. (SCIIF: 13.709, 5 Years IF: 14.82; Ranking 12/285; Materials Science, Multidisciplinary, citation: 69).
  12. Huang, L.-C. S., Chuang, H., Kapoor, M., Hsieh, C.-Y., Chou, S.-C., Lin, H.-H., Chen, Y.-W., Chang, C.-C., Hwu, J.R.*, Liang, Y.-C.*, Hsu, M.-H.* (2015) Development of Nordihydroguaiaretic Acid Derivatives as Potential Multidrug-Resistant Selective Agents for Cancer Treatment, RSC Advance 5, 107833-107838. (SCI IF: 2.936; 5 Years IF: 3.096; Ranking 71/171, Chemistry, Multidisciplinary; Citation: 1)
  13. Chu, H.-L., Chiu, S.-C., Sung, C.-F., Tseng, W., Chang, Y.-C., Jian, W.-B.*, Chen, Y.-C.*, Yuan, C.-J., Li, H.-Y., Gu, F., Di Ventra, M.; Chang, C.-C.* (2014) Programmable redox state of nickel ion chain in DNA, Nano Letters 14, 1026-1031. (SCI IF: 12.08; 5 year IF: 14.201; Ranking 9/146, Physics, Applied; citation 11).
  14. Cheng T.-M., Murad Y. M., Chang C.-C.*, Yang M.-C., Baral T. N., Cowan A., Tseng S.-H., Wong A., MacKenzie R., Zhang J.* (2014) Single domain antibody against carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) inhibits proliferation, migration, invasion and angiogenesis of pancreatic cancer cells, European Journal of Cancer 50, 713-721. (SCI IF: 7.191; 5 year IF: 6.759; Ranking 25/223, Oncology; citation 5)
  15. Hsu M.-H.*, Chuang, H., Cheng, F.-Y., Huang, Y.-P., Han, C.-C., Chen, J.-Y, Huang, S.-C., Chen, J.-K., Wu, D.-S., Chu, H.-L., Chang, C.-C. (2014) Directly thiolated modification onto the surface of detonation nanodiamonds, ACS Appl. Mater. Interfaces. 6, 7198–7203 (IF: 8.097; 5 years IF: 8.284; Ranking: 15/92, Nanoscience & Nanotechnology; Ranking: 26/285, Materials Science, Multidisciplinary; Citation 22)
  16. Chu H.-L., Chen H.-W., Tseng S.-H., Hsu M.-H., Ho L.-P., Chou F.-H., Li H.-Y., Chang Y.-C., Chen P.-H., Tsai L.-Y., Chou C.-C., Chen J. S., Cheng T.-M*, Chang C.-C.* (2014) Development of growth hormone conjugated nanodiamond complex for cancer therapy, ChemMedChem 9, 1023-1029 (SCI IF: 3.009; 5 year IF: 2.931; Ranking 96/261, Pharmacology & Pharmacy; Citation 9).
  17. Chu H.-L., Chen T.-H., Wu C.-Y., Yang Y.-C., Tseng S.-H., Cheng T.-M., Ho L.-P., Tsai L.-Y., Li H.-Y., Chang C.-S., Chang C.-C.* (2014) Thermal stability and folding kinetics analysis of disordered protein securin. Journal of Thermal Analysis and Calorimetry, J. Therm. Anal. Calori., 115, 2171-2178 (SCI IF: 2.209; 5 year IF: 1.917; Ranking 18/59, Thermodynamics; Citation 4).
  18. Hsu M.-H.*, Chuang H., Cheng F.-Y., Huang Y.-P., Han C.-C., Pao K.-C., Chou S.-C., Shieh F.-K., Tsai F.-Y., Lin C.-C., Wu D.-S. and Chang C.-C., (2014) Simple and highly efficient direct thiolation of the surface of carbon nanotubes, RSC Advances 4, 14777–14780 (SCI IF: 2.936; 5 Years IF: 3.096; Ranking 71/171, Chemistry, Multidisciplinary; Citation: 8)
  19. Chu H.-L., Cheng T.-M., Chen H.-W., Chou F.-H., Chang Y.-C., Lin H.-Y., Liu S.-Y., Liang Y.-C., Hsu M.-H., Wu D.-S., Li H.-Y., Ho L.-P., Wu P.-C., Chen F.-R., Chen G.-S., Shieh D.-B., Chang C.-S., Su C.-H., Yao Z., and Chang C.-C.* (2013) Synthesis of apolipoprotein B lipoparticles to deliver hydrophobic/amphiphilic materials. ACS Appl. Mater. Interfaces. 5, 7509-7516. (IF: 8.097; 5 years IF: 8.284; Ranking: 15/92, Nanoscience & Nanotechnology; Ranking: 26/285, Materials Science, Multidisciplinary; Citation 6)
  20. Li H.-Y., Tseng S.-H., Cheng T.-M., Chu H.-L., Lu Y.-N., Wang F.-Y., Tsai L.-Y., Shieh J.-Y., Yang J.-Y., Juan C.-C., Tu L.-C., Chang C.-C.* (2013) Rapid and highly sensitive detection of Enterovirus 71 by using nanogold-enhanced electrochemical impedance spectroscopy. Nanotechnology 24, 285102. (SCI IF: 3.404; 5 Years IF: 3.467; Ranking 30/146, Physics, Applied; Citation: 3).
  21. Yu S.-Y., Liu H.-F., Wang S.-P., Chang C.-C., Tsai C.-M., Chao J.-I.* (2013) Evidence of securin-mediated resistance to gefitinib-induced apoptosis in human cancer cells, Chemico-Biological Interactions 23, 412-422. (SCI IF: 3.296; 5 Years IF: 3.308; Ranking 24/94, Toxicology; Citation: 9).
  22. Svanidze A.V., Koludarov I.P., Lushnikov S.G., Asenbaum A., Pruner C., Aliev F. M., Chang C.-C., Kan L.-S. (2012) Specific features of the temperature behavior of lysozyme diffusivity in solutions with different protein concentrations. J. Mol. Liquids 168, 7-11(SCI IF: 4.513; 5 Years IF: 3.929; Ranking 6/37, PHYSICS, ATOMIC, MOLECULAR & CHEMICAL; Citation: 1)
  23. Qin W., Sundaram M., Wang Y., Zhou H., Chang C-C, Manhas S., Yao E. F., Jiang Z. G., Wang C., Figeys D., Jia W., and Yao Z (2011) Missense mutation in APOC3 within the C-terminal lipid-binding domain of human apoC-III results in impaired assembly and secretion of triacylglycerol-rich very low density lipoproteins: Evidence that APOC-III plays a major role in the formation of lipid precursors within the microsomal lumen. J. Biol. Chem. 286, 27769-27780 (SCI IF: 4.011; 5 Years IF: 4.254; Ranking 75/293, Biochemistry & Molecular Biology; Citation: 55)
  24. Tseng S-H, JangJian P-C, Tsai C-M, Cheng T-M, Chu H-L and Chang C-C* (2011) Ni2+ enhanced charge transport via p-p stacking corridor in metallic-DNA. Biophysical J. 100, 1042-1048. (SCI IF: 3.632; 5 Years IF: 3.668; Ranking 18/72, Biophysics; Citation: 11)
  25. Cheng T-M, Tseng S-H, Lee T-C, Pan J-P, Mao S. J.T., Chang C-C* (2011) Human haptoglobin phenotypes and concentration determination by nanogold-enhanced electrochemical impedance spectroscopy, Nanotechnology, 22, 245105. (SCI IF: 3.404; 5 Years IF: 3.467; Ranking 30/146, Physics, Applied; Citation: 8)
  26. Cheng, T.-M., Mao, S. J.T., Lai S.-T., Chang C.-C., Yang M.-C., Chen N.-C., Chou S.-C., Pan J.-P. (2011) Hemoglobin-induced oxidative stress is associated with both endogenous peroxidase activity and H2O2 generation from polyunsaturated fatty acids. Free Radical Research 45, 303-316 (SCI IF: 3.038; 5 Years IF: 3.136; Ranking 137/293, Biochemistry & Molecular Biology; Citation: 6)
  27. Liu YK, Lin YL, Chen CH, Lin CM, Ma KL, Chou FH, Tsai JS, Lin HY, Chen FR, Cheng TL, Chang C-C, Liao KW. (2011) A unique and potent protein binding nature of liposome containing polyethylenimine and polyethylene glycol: a nondisplaceable property. Biotechnol Bioeng,108, 1318-1327. (SCI IF: 3.952; 5 Years IF: 4.206; Ranking 32/161, Biochemistry & Molecular Biology; Citation: 6)
  28. Lin C.-Y., Huang Y.-S., Li C.-H., Hsieh Y.-T., He P.-J., Hsu W.-T., Yeh Y.-C., Chiang F.-H., Wu M.-S., Chang C.-C., Liao K.-W.* (2009) Characterizing the polymeric status of Helicobacter pylori heat shock protein 60. Biochem. Biophys. Res. Commun 388,283-289. (SCI IF: 2.559; 5 Years IF: 2.455; Ranking 35/72, Biophysics; Citation: 12)
  29. Jangjian P.C., Liu T-F, Tsai C.-M., Li M.-Y., Tsai M.-S.,Tseng S.-H., Cheng T.-M. and Chang C.-C.* (2009) DNA mismatch detection by metal ion enhanced impedance analysis. Chinese J. Physics 47, 740-747. (SCI IF: 1.051; 5 Years IF: 0.821; Ranking 51/78, Physics, Multidisciplinary; Citation: 5)
  30. Li M, Huang Y-S, Jeng U-S*, Hsu I-J*, Wu Y-C-S, Lai Y-H, Su C-H, Lee J-F, Wang Y, and Chang C-C (2009) Resonant X-ray Scattering and Absorption for the Global and Local Structures of Cu-modified Metallothioneins in Solution. Biophysical J. 97, 609-617. (SCI IF: 3.632; 5 Years IF: 3.668; Ranking 18/72, Biophysics; Citation: 9)
  31. Liu C.-P., Wey M.-T., Chang C.-C.*, Kan L.-S. (2009) Direct observation of single molecule conformational change of tight-turn paperclip DNA triplex in solution. Applied Biochemistry and Biotechnology. 159, 261-269. (SCI IF: 1.797; 5 Years IF: 1.919; Ranking 102/161, Biotechnology & Applied Microbiology; Citation: 1)
  32. Jang Jian P.-C., Liu T.-F., Li M.-Y., Tsai M.-S., Chang C.-C.* (2009) Room temperature negative differential resistance in DNA-based molecular devices. Applied Physics Letters. 94, 043105 (2009) This paper has been selected for publication in Virtual Journal of Biological Physics Research (2009) and This paper has been selected for publication in Virtual Journal of Nanoscale Science & Technology (2009) (IF: 3.495; 5 Years IF: 3.386; Ranking 29/146, citation 24)
  33. Chang C.-C.*,Chen P.-H.,Chu H.-L.,Lee T.-C., Chou C.-C., Chao J.-I., Su C.-Y., Chen J. S.,Tsai J.-S.,Tsai C.-M., Ho Y.-P., Sun K.-W., Cheng C.-L., Chen F.-R. (2008) Laser induced popcornlike conformational transition of nano-diamond as a nanoknife. Applied Physics Letters. 93, 033905. This paper has been selected for publication in Virtual Journal of Biological Physics Research (2008) (IF: 3.495; 5 Years IF: 3.386; Ranking 29/146, citation 10)
  34. JangJian P.-C., Liu T.-F., Tsai C.-M., Tsai M.-S., Chang C.-C.* (2008) Ni2+ doping DNA: a semiconducting biopolymer. Nanotechnology 19, 355703. (SCI IF: 3.404; 5 Years IF: 3.467; Ranking 30/146, Physics, Applied; Citation 8)
  35. Liu K.-K., Chen M.-F., Chen P.-Y., Lee T. J.F., Cheng C.-L., Chang C.-C., Ho Y.-P. ,Chao J.-I. (2008) Alpha-bungarotoxin binding to target cell in a developing visual system by carboxylated nanodiamond. Nanotechnology, 19 205102. (SCI IF: 3.404; 5 Years IF: 3.467; Ranking 30/146, Physics, Applied; Citation 45)
  36. Chang C.-C.*, LinP.-Y.,Chen Y.-F, Chang C.-S., Kan L.-S. (2007) Direct visualization of triplex DNA molecular dynamics by fluorescence resonance energy transfer and atomic force microscopy measurements. Applied Physics Letters 91, 213901; This paper has been selected for publication in Virtual Journal of Biological Physics Research (2007) (IF: 3.495; 5 Years IF:3.386; Ranking 29/146, citation 4)
  37. K.W. Sun* and C.C. Chang (2007) Patterning of magnetic molecular self-assembly on semiconductor substrates. Journal of Physics and Chemistry of solids 68, p.1211-1214. (IF 2.207; 5 Years IF:3.386; Ranking:85/171)
  38. Liu, K.-K., Cheng, C.-L., Chang, C.-C., and Chao, J.-I.* (2007) Biocompatible and detectable carboxylated nanodiamond on human cell. Nanotechnology. 18 (2007) 325102. (IF: 3.404; 5 Years IF:3.467; Ranking:30/146, citation 169)
  39. Chao J.-I, Perevedentseva E., Chung P.- H., Liu K.- K., Cheng C.-Y., Chang C.- C., Cheng C. – L*. (2007) Nanometer-sized diamond particle as a probe for biolabeling. Biophysics J. 93, 2199-2208. Cover Story. This paper has been selected in The Virtual Journal of Nanotechnology Environment, Health and Safety (2007) (IF: 3.495; 5 years IF: 3.711; 18/72, citation 183)
  40. Chang C.-C*. and Kan L.-S. (2007) Protein folding: an antagonistic reaction of spontaneous folding and diffusion limited aggregation in nature. Chinese. J. Phys. 45, 693-702. (SCI IF: 1.051; 5 Years IF: 0.821; Ranking 51/78, Physics, Multidisciplinary; Citation 1)
  41. Hsiao P.-W., Chang C.-C., Liu H.-F., Tsai C.-M., Chiu T.-H., and Chao J.-I (2007) Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. Toxicology and Applied Pharmacology. 222, 97-104. (IF: 3.616; 5 Years IF:3.906; Ranking 20/94, citation 35)
  42. Cheng C. – Y., Perevedentseva E., Tu J. – S., Chung P. – H., Cheng C. – L*., Liu K.-K., Chao J.-I.*, Chen P.-H., Chang C.-C.* (2007) Direct and In vitro observation of growth hormone receptor molecules in A549 human lung epithelial cells by nanodiamond labeling. Applied Physics Letters, 90, 163903. (SCI). This paper has been selected in Virtual Journal of Biological Physics Research (2007) (IF: 3.495; 5 Years IF:3.386; Ranking 29/146, citation 75)
  43. Chang C.-C, Sun K.-W. *, Lee S.-F., Kan L.-S (2007) Self-assembled Molecular Magnets on Patterned Silicon Substrates: Bridging Bio-molecules with Nanoelectronics. Biomaterials 28, 1941-7. (SCI) Leading opinion. (IF: 8.806; 5 Years IF:9.315; Ranking 1/78, Engineering, Biomedical, Citation 9)
  44. Chang C.-C, Sun K.-W., Kan L.-S, Kuan C.H. (2006) Guided Three-dimensional Molecular Self-assembly on Silicon Substrates. Applied Physics Letters 88, 263104. This paper has been selected for the Volume 14, Issue 2 of Virtual Journal of Biological Physics Research. This paper has been selected for the Volume 12, Issue 1, 2006 issue of Virtual Journal of Nanoscale Science & Technology, too. (SCI) (IF: 3.495; 5 Years IF:3.386; Ranking 29/146)
  45. Chang C.-C*, Lee S.-F.; Sun K.-W., Ho C.-C.; Chen Y.-T.; Chang C.-H., Kan L.-S. (2006) Mn,Cd-metallothionein-2: A room temperature magnetic protein. Biochem. Biophys. Res. Commun. 340, 1134-1138. (SCI IF: 2.559; 5 Years IF: 2.455; Ranking 35/72, Biophysics; Citation 6)
  46. Chang C.-C*., Lin C.-S.,Chen M.-C.,Liu Y.-C., Huang Y.-F., Lin P.-Y.,Chen Y.-F, Chang C.-S., Kan L.-S.(2006) Folding and Structural Characterization of Recombinant Cyclin-dependent Kinase Inhibitor p21(Cip1, Waf1, Sdi1), Biophysical Reviews and Letters. 1, 45-56. (citation 3 by google scholar)
  47. Chung P.-H., Perevedentseva E., Tu J.-S., Chang C.-C.,Cheng C.-L. (2006) Spectroscopic study of bio-functionalized nanodiamonds. Diamond and Related Materials. 15, 622-625. (SCI IF: 2.232; 5 Years IF: 2.209; Ranking: 124/285, citation 143)
  48. Chang CC*, Lin PY, Yeh XC, Deng KH, Ho YP and Kan LS* (2005) Protein folding stabilizing time measurement: a direct folding process and three-dimensional random walk simulation. Biochem. Biophys. Res. Commun. 328, 845-850. (SCI IF: 2.559; 5 Years IF: 2.455; Ranking 35/72, Biophysics; Citation 6)
  49. Chang CC*, Yeh XC, Lee HT, Lin PY, Kan LS*(2004) Refolding of lysozyme by quasistatic and direct dilution reaction paths: A first-order-like state transition. Physical Review E.70, 011904 (SCI) (NSC 92-2112-M-259-016) This paper has been selected for the Virtual Journal of Biological Physics Research 8, issue 2 (July 15, 2004). (IF:2.284; 5 Years IF: 2.293; Ranking: 7/55, Physics, Mathematical; Citation 11)
  50. Chang CC*, Cheng MS, Su YC, and Kan LS* (2003) A first-order-like state transition for recombinant protein folding. J. Biomol. Struct. Dyn. 21, 247~255. (IF:3.107; 5 Years IF: 2.443; Ranking: 129/293, Biochemistry & Molecular Biology, Citation 9)
  51. Liu YL, Lee HT, Chang CC *, and Kan LS * (2003) Reversible folding of cysteine-rich metallothionein by an over-critical reaction path. Biochem. Biophys. Res. Commun. 306, 59-63. (SCI IF: 2.559; 5 Years IF: 2.455; Ranking 35/72, Biophysics; Citation 13)
  52. Chen HM, Chan SC, Lee JC, Chang CC, Murugan M, Jack RW. (2003) Transmission electron microscopic observations of membrane effects of antibiotic cecropin B on Escherichia coli. Microsc Res Tech. 62, 423-430. (SCI IF: 1.087; 5 Years IF: 1.134; Ranking 59/85, Biology; Citation 22)
  53. Chang CC*, Su YC, Cheng MS and Kan LS* (2002) Protein folding by quasi-static-like process-a first order state transition. Physical Review E 66, 021903 (SCI). This paper has been selected for the Virtual Journal of Biological Physics Research. (IF:2.284; 5 Years IF: 2.293; Ranking: 7/55, Physics, Mathematical; Citation 14)
  54. Chang,CC, Tsai, CT and Chang, CY (2002) Structural restoration of inactive recombinant fish growth hormones by chemical chaperonin and solvent restraint approaches. Protein Engineering 15: 437-441. (IF:2.065; Ranking: 44/132, Biotechnology & Applied Microbiology; Citation 9)
  55. Tzang BS, Lai YC, Hsu M, Chang HW, Chang CC, Huang PC and Liu YC (1999) Function and sequence analyses of tumor suppressor gene p53 of CHO.K1 cell. DNA and Cell Biol. 18:315-321. (IF:2.634; 5 Years IF:2.029; Ranking: 88/171, citation 31)
  56. Chang CC, Liao WF and Huang PC (1998) Cysteine contributions to binding preference for Zn/Cd in b-domain of metallothionein. Protein Engineering 11: 40-46. (IF:2.065; Ranking: 44/132, Biotechnology & Applied Microbiology; Citation 18)
  57. Chang CC and Huang PC (1996) Semi-empirical simulation of Zn/Cd binding site preference in the metal binding domains of mammalian metallothionein. Protein Engineering 9:1165-1172. (IF:2.065; Ranking: 44/132, Biotechnology & Applied Microbiology; Citation 26 )
  58. Liu YC, Chen GS and Chang CC (1995) Mutation of gene required for cell spreading is corrected by serum or factor secreted by normal cells. In Vitro Cell Dev. Biol.-Animal 31: 571-573. (SCI) (IF:1.447; 5 Years IF:1.36; Ranking: 36/42, Developmental Biology)

Other Peer Reviewed papers and book chapters:

  1. KW Sun and C-C Chang (2011) Bridging Biomolecules with Nanoelectronics in “Handbook of Nanophysics: Nanoelectronics and Nanophotonics” Taylor & Francis Group.
  2. JangJian P.-C., Tseng S.-H., Tsai C.-M., Cheng T.-M., Chu H.-L. and Chang C.-C. *. (2010) DNA: a native nano-wire in nature. Instruments Today, 177, 61-71.
  3. J.I. Chao, E. Perevedentseva, C.C. Chang, C.Y. Cheng, K.K. Liu, P.H. Chung, J.S. Tu, C.D. Chu, S.J. Cai, and C.L. Cheng (2010) Protein–Nanodiamond Complexes for Cellular Surgery: Nanodiamond and Its Bioapplications Using the Spectroscopic Properties as Probe for Biolabeling. In Nanodiamonds:Applications in Biology and Nanoscale Medicine (D Ho Ed.), pp 189-224. Springer, New York. (Citation 4)
  4. W. K. Liu, A. Adnan, A. M. Kopacz, M. Hallikainen, D. Ho, R. Lam, J. Lee, T. Belytschko, G. Schatz, Y.H. T. Tzeng, Y.-J. Kim, S. Baik, M. K. Kim, T. Kim, J.H. Lee, E.-S. Hwang, S. Im, E. Ōsawa, A. Barnard, H.-C. Chang, C.-C. Chang, and E. Oñate (2010) Design of Nanodiamond Based Drug Delivery Patch for Cancer Therapeutics and Imaging Applications, pp 249-284. Springer, New York. (Citation 8)
  5. Chang CC*, Chen P.H, Yeh YC, Tsai CM, Su JY, Chen JS (2007) The application of nano particles in biomedicine. Instruments Today, 28, 27-37.
  6. Yang CH, Wang CY, Chen KC, Chang CC, Sun KW (2007)利用分子自組裝製造新穎生物材料;電子月刊.138, 182-190.
  7. Chang C-C* (2006) Protein folding and aggregation. 物理雙月刊, 28, 668-675.
  8. 張家靖,陳冠舟,孫建文(2006) 矽基版表面蛋白質奈米柱之自組裝, Chemistry (The Chinese Chem. Soc., Taipei), 64, 477-482.
  9. Chang C-C*, and Kan L.-S. (2005) Manipulation and Characterization of Nano-Biomolecules, Symposium on Nano Device Technology 2005. pp95~98.
  10. Chang CC and Huang PC (1999) Simulation of Zn/Cd binding in mammalian metallothionein domains. In Metallothionein IV (Klaassen CD ed.) Pp 45-49. Birkhauser Verlag publish, Boston. (Citation 2)
  11. Chang CC, Chou YC, and Wu WG (1994) SERS study of the transport of ATP through the DPPC bilayer. Proc. Natl. Sci. Counc. ROC(A)18: 163-167.
  12. Huang JK and Chang CC (1994) Computer simulation of enzymatic reactions. Chemistry (Taiwan) 52: 246-250.